recital schreef op 9 augustus 2018 16:03:
EMA has issued a notice about a shortage of Shire’s Cinryze. The C1 inhibitor could temporarily be in short supply in 11 European countries. Shire attributed the shortage of the hereditary angioedema drug to an increase in demand that exceeds its current production capacity. Work to increase output is underway, but in the meantime EMA wants prescribers to consider alternatives. EMA Notice